The analysis of urogenital Mycoplasma infection and drug resistance

doi:10.3969/j.issn.1674-7151.2015.02.009

Abstract：Objective To investigate the infection and drug resistance of Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) in Zhengzhou. Methods 13 331 patients were collected in our hospital from July 2012 to June 2013 for Uu and Mh detection. All patients were divided into ≤18 age group, 19~30 age group, 31~40 age group, 41~50 age group, 51~60 age group and≥61 age group. Uu, Mh and Uu+Mh of all patients were detected, and drug resistance were analyzed. Results The Mycoplasma infection rate in 13 331 samples was 50.57%(6741/13 331), and the highest constituent ratio was Uu(85.85%, 5787/6741). The difference of Uu infection rates and the mixed infection rates among different ages groups were significant (Pall<0.05), while the difference of Mh infection rates among different ages groups was not significant. The highest positive rate of Uu was 19~30 age group (45.10%), the highest positive rate of Mh was ≥ 61 age group (1.52%), and the highest rate of Uu+Mh was 51~60 age group (9.31%). Compared with Mh and mixed infection, drug resistance of Uu was less serious. Tetracyclines antibiotic sensitive rate for Mycoplasma were more than 90%. Excepted josamycin, erythromycins were sensitive for Uu but not for Mh. Quinolones were resistant in varying degrees for Uu and Mh and antibiotic screening test should be done. Conclusion The infection rate of Mycoplasma in the people who likely had urogenital tract infection is 50.57%in Zhengzhou. Uu infection is distributed mainly from 19~50 age and the mixed infection is distributed mainly from 41~60 age. For treatment, we can use Tetracyclines as the first choice drug in this area. At the same time, antibiotic screening test also should be done for drug resistance control.