The clinical value of serum cystatin C and urinary micro-albumin detection in the diagnosis of early renal function damage in children with henoch-schonlein purpura
ZHAI Kai-qi
ZHANG Li-na
ZHANG Han-tao
Abstract：Objective To explore the clinical value of serum cystatin C(CysC) and urinary micro-al-bumin(mALB) detection in the diagnosis of early renal function damage in the children with henoch-schonlein purpura (HSP). Methods 120 cases of HSP children from January 2014 to December 2014 in our hospital department of dermatology were collected. They were divided into normal renal function group (60 cases) and renal dysfunction group(60 cases) according to their renal function. In the same time, 60 healthy children were chosen as control group. The levels of serum CysC and urine mALB of all the children were detected and the re-sults were analyzed statistically. Results There were statistical significance in the differences of serum CysC and urine mALB levels among control group, normal renal function group and renal dysfunction group (F=7.13, F=8.54, Pall<0.05). The serum CysC and urine mALB levels in normal renal function group and renal dysfunction group were all higher than that of control group , and the differences all had statistical significance (Pall<0.05). The serum CysC and urine mALB levels in renal dysfunction group were all higher than that of normal renal function group, and the differences all had statistical significance(Pall<0.05). The positive rates of serum CysC, urine mALB and combine detection in HSP group were all higher than that of control group, and the differences all had statistical significance (Pall<0.05). The positive rates of serum CysC and urine mALB were all lower than that of combine detection, and the differences all had statistical significance (Pall<0.05). Conclusion The serum CysC and urine mALB can be used as the index for the diagnosis of early renal function in the children with HSP.
Keywords：Henoch-schonlein purpuraEarly renal damageUrinary micro-albuminSerum cystatin CChildren
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 97-99 )