The significance of AFP,FER and CA19-9 combine detection in primary hepatic carcinoma diagnosis
WANG Shu-feng
ZHOU Li-li
Abstract：Objective To assess the clinical significance of alpha-fetoprotein (AFP), ferritin (FER) and carbohydrate antigen 19-9 (CA19-9)combine detection in diagnosis of primary hepatic carcinoma (PHC). Methods 91 cases PHC patients, 57 cases hepatic cirrhosis patients and 95 cases healthy controls from March 2013 to March 2014 in our hospital were collected. The levels of AFP , FER and CA19-9 of all subjects were detected, and the results were analyzed statistically. Results There were statistical significance in the differences of AFP, FER and CA19-9 levels among three groups (Pall<0.05). The AFP, FER and CA19-9 levels in PHC group and hepatic cirrhosis group were all higher than that of control group , and the differences all had statistical significance (Pall<0.05). The AFP, FER and CA19-9 levels in PHC group were all higher than that of hepatic cirrhosis group, and the differences all had statistical significance (Pall<0.05). There were statistical significance in the differences of AFP, FER, CA19-9 and combine detection positive rate in PHC group and hepatic cirrhosis group (Pall<0.05). The positive rate of combine detection in PHC group and hepatic cirrhosis group were all higher than that of AFP, FER and CA19-9 lonely detection, and the differences all had statistical significance(Pall<0.05). Conclusion The combine detection of AFP, FER and CA19-9 can improve the detection rate of PHC, and which have an important role in disease screening and differential diagnosis.
Keywords：Alpha-fetoproteinFerritinCarbohydrate antigen 19-9Primary hepatic carcinomaCombine detection
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 39-41 )