The correlation of vitamin D, HbA1c and HOMA-IR in patients with type 2 diabetes mellitus
HU Juan-yu
LI Li
Abstract：Objective To discuss the relation of vitamin D with hemoglobin A1c (HbA1c) and HOMA-IR in patients with type 2 diabetes mellitus (T2DM). Methods 75 cases T2DM patients (research group) and 50 cases healthy people (control group) were collected in our hospital from March 2014 to August 2014. The fasting plasma glucose(FPG), fasting insulin(FIN), HbA1c, 25-hydroxy vitamin D3[25-(OH)D3] levels of all subjects were detected and HOMA-IR was calculation , all data were analyzed statistically. Results The levels of FPG, FIN, HbA1c and HOMA-IR in T2DM group were all higher than that of control group, and the differences all had statistical significance(Pall<0.05). The level of 25-(OH)D3 in T2DM group was lower than that of control group, and the difference had statistical significance (P<0.05). The level of 25-(OH)D3 had negative correlation with HbA1c and HOMA-IR(r=-0.548, r=-0.454, Pall<0.05). Conclusion The level of serum VitD has a remarkably decrease in T2DM patients , and has negative correlation with HbA1c level and HOMA-IR.
Keywords：Vitamin DHemoglobin A1cType 2 diabetes mellitusInsulin resistance
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 36-38 )