Characteristics of clinical distribution and analysis of susceptibility test in Acinetobacter baumannii clinical isolates

doi:10.3969/j.issn.1674-7151.2014.02.010

Abstract：Objective To investigate clinical distribution and drug resistance of Acinetobacter bau-mannii in our hospital so as to provide evidence for clinical prevention and treatment programs. Methods Species identification of clinical isolates from Jun. 2013 to Dec. 2013 was performed using VITEK 2 compact instrument. The susceptibility of Acinetobacter baumannii isolates to 17 antibiotics was determined using VITEK 2 AST-GN13 card. The clinical datas and the results were analyzed. Results Of 627 Acinetobacter spp., there were 541 strains of Acinetobacter baumannii isolated with the detection rate of 86.3%(541/627). The patients older than 50 years were in the majority for clinical Acinetobacter baumannii infection in our hos-pital with the distribution rate of 84.1%(455/541). The highest relevance ratio of specimen was sputum with the rate of 85.2%(461/541). ICU separation rate (35.7%, 193/541) was the highest and followed by depart-ment of respiratory medcine (25.5%, 138/541). To 17 kinds of common clinical antibacterials, the resistance rate of imipenem was the lowest (28.8%), other antimicrobial resistance rates were higher than one third. The rate for multiple drug resistance was 64.5%(349/541). Conclusion The main species is Acinetobacter bau-mannii among Acinetobacter spp. clinical isolates. Acinetobacter baumannii clinical isolates mainly cause el-derly and intensive care patients suffer from respiratory tract infection, and show high level of drug resistance, significantly high detection rate of multiple drug resistance phenotype.