Relationship Between Osteoarthritis and Neutrophils Based on Bibliometrics

Wang Yonghong; Zhang Xiaopeng

Abstract：Objective This paper provides a comprehensive analysis of the field of osteoarthritis and neutrophil correlation research and discusses research hotspots and future prospects.Methods We retrieved all articles on osteoarthritis and neutrophil correlation research from the Web of Science Core Collection database,analyzed and visualized their publication characteristics,country/region and institution,authors,journals,references,and keywords using CiteSpace(6.3 R1),VOSviewer(version 1.6.18),and bibliometrix(version 4.1.3).Results We extracted a total of 590 articles for analysis,with a steady increase in annual publications and citations.The United States is the largest paper producing country.Koch Ae published the most papers(10).Rheumatoid arthritis,osteoarthritis,inflammation,synovial fluid were the main keywords in the field.Cluster analysis showed that microbial transport and innate immunity are current research hotspots.Conclusion The correlation between osteoarthritis and neutrophils is increasingly being studied.Neutrophils play an integral role in the development of osteoarthritis and suggest the prognosis of the disease.Immunotherapy targeting neutrophils also has great potential.