The Early Therapeutic Efficacy of Olif-Assisted Lateral Interbody Fusion with Plate Internal Fixation for Grades Ⅰ、Ⅱ Lumbar Spondylolisthesis

Shi Ming; Li Song; Luo Man; Zhang Dan; Wei Yangfei; Cao Junjun

Abstract：Objective To assess the early clinical effectiveness and safety of oblique lateral interbody fusion(OLIF)augmented by lateral plate internal fixation in the management of lumbar spondylolisthesis grades Ⅰ、Ⅱ.Methods A retrospective analysis was performed on clinical data from 54 patients with lumbar spondylolisthesis,treated at the International Zhuang Medicine Hospital affiliated with Guangxi University of Chinese Medicine between June 2020 and June 2023.Based on surgical techniques,patients were categorized into two groups:The observation group(21 patients)undergoing lateral plate internal fixation-assisted OLIF,and the control group(33 patients)receiving traditional posterior decompression and fusion internal fixation surgery.The observation group included 11 males and 10 females,aged 55 to 82 years,with a mean age of(64.20±8.90)years.The control group included 15 males and 18 females,aged 55 to 58 years,with a mean age of(64.80±8.70)years.Comparative analysis was conducted on surgery duration,intraoperative blood loss,postoperative drainage volume,and hospital stay between the groups.The lumbar function was evaluated using the pain visual analogue scale(VAS),Oswestry disability index(ODI),and Japanese orthopedic association(JOA)spinal scores before surgery and at 1 week,4 weeks,and 6 months postoperatively.Results All patients completed a follow-up period exceeding 6 months.Significant differences were observed between the groups in surgery duration,intraoperative blood loss,postoperative drainage volume,and hospital stay(P＜0.05).Postoperatively,the observation group exhibited lower VAS scores for lower back pain at 1 week and 4 weeks compared to the control group(P＜0.05).At 4 weeks postoperatively,the observation group had higher JOA scores than the control group(P＜0.05).Additionally,the observation group showed lower ODI scores at 1 week and 4 weeks postoperatively compared to the control group(P＜0.05).The complication incidence was 4.76％in the observation group and 9.09％in the control group,with no statistically significant difference between the groups(P＞0.05).Conclusion Compared to traditional posterior decompression and fusion internal fixation surgery,lumbar lateral plate internal fixation-assisted OLIF for lumbar spondylolisthesis grades Ⅰ、Ⅱ demonstrates superior early clinical effectiveness and safety,with reduced surgical trauma,less intraoperative and postoperative bleeding,shorter hospital stay,earlier pain relief,and enhanced lumbar function.