The Clinical Study of Intradiscal Cement Leakage after Percutaneous Kyphoplasty

Abstract：Objective To study the effect of intradiscal cement leakage on the degeneration of cement-leaking discs and the interim clinical efficacy after percutaneous kyphoplasty (PKP).Methods We retrospectively analyzed 188 cases of patients from March 2009 to September 2014 with the admittance to Liaoyang Central Hospital,diagnosed as thoracolumbar vertebral compression fractures,including 3 2 males and 1 5 6 females with average age of 6 9.1 years (range,62～78 years).All were treated by PKP,classified into 26 cases with intradiscal cement leakage (Study Group) and 162 cases without cement leakage (control group).All cases were followed with an average of 25.2 months.The degeneration of discs was assessed using anterior disc height and posterior disc height on standard lateral radiographs.Clinical ef ficacy was assessed using the Oswestry Disability Index scores(ODI) and Visual Analog Scale(VAS).The changes of disc height and the ODI and VAS score were compared between the two groups.Results Anterior disc height and posterior disc height of Study Group at the last follow-up:(5.65±2.21)mm、(2.94±0.89)mm;Those of control group:(7.36±2.43) m m、(3.77±1.84)mm.The disc height of the study group was significantly lower than the control group (P＜0.05).The ODI and VAS score of two groups before surgery:(72.98± 12.42) ％、(7.50± 1.05);(69.13 ± 13.05) ％、(7.44±0.97).The ODI and VAS score of two groups one day after surgery:(26.80±4.75)％、(2.45±0.63);(25.95± 5.07)％、(2.47±0.77).The ODI and VAS score of two groups at the last follow-up:(31.12±3.58) ％、(2.81±0.72);(29.75 ± 4.32)％、(2.76 ±0.70).The ODI and VAS score of two groups were significantly improved after operation and continued to the last follow-up,and there was no significant difference between the two groups (P＞0.05).Conclusion Intradiscal cement leakage can accelerate the degeneration of the intervertebral disc,but it does not affect the interim clinical efficacy after PKP.