Height Restoration of Compressed Vertebrae after Percutaneous Vertebroplasty with Medium-viscosity Cement and High-viscosity Cement in the Treatment of Osteoporotic Vertebral Compression Fractures

Abstract：Objective To compare the clinical efficacy of medium-viscosity cement with high-viscosity cement per-cutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures to restore compressed verte-brae height.Methods Enrolled for this study were 158 vertebrae with osteoporotic vertebral compression fracture who had been treated by PVP in our department from Oct.2011 to Mar.2014 and followed up for at least two year.The ce-ment volume inj ected were recorded.The anterior vertebral heights and the kyphosis angle were measured preoperative, post operative and at follow-up.They were randomly assigned into two groups according to the bone-cements they used. Postoperative vertebral height restoration,kyphosis correction were compared.Results The average cement volume in-jected was (4.2±1.6)mL,the average anterior height was (17.8±5.7)mm,cobb angle was (20.3±6.7)°before opera-tion,and the average anterior height was (22.2±4.2)mm,cobb angle was (13.8±4.8)°after operation.The average an-terior height was (22.0±4.5)mm,cobb angle was (13.1±5.2)°at follow-up,and anterior compression improvement was (15.1±9.6)%,cobb angle correction degree was (-6.7±5.5)°in the medium-viscosity cement group.The average cement volume injected was (4.8±1.5)mL,the average anterior height was (17.1±5.5)mm,cobb angle was (21.8±6. 5)°before operation,and the average anterior height was (23.6±4.7)mm,cobb angle was (12.8±5.4)°after operation and the average anterior height was (23.3±4.8)mm,cobb angle was (12.8±5.4)°at follow-up,and anterior compres-sion improvement was (20.7±12.1)%,cobb angle correction degree was (-9.4±7.5)°in the high-viscosity cement group.There were no significant differences between these 2 groups in bone cement volume injected(P>0.05).The av-erage anterior height,cobb angle at postoperation were significantly improved after operation in both groups (P<0. 05).The anterior compression improvement and cobb angle correction degree of high-viscosity cement group were sig-nificantly better than the medium-viscosity cement group (P<0.05).Conclusion Both medium-viscosity cement and high-viscosity cement PVP can restore vertebra height and improve kyphosis for the treatment of osteopo rotic verte-bral compression fractures,whereas high-viscosity cement PVP is more effective in vertebral height restoration.