Imaging Diagnosis of Spine Eosinophilic Granuloma in Children

Abstract：Objective To study the imaging findings of spine eosinophilic granuloma(EG)in children. Methods The imaging findings of 12 patients with eosinophilic granuloma of spine confirmed by surgery were analyzed retrospectively. 12 ca-ses were underwent DR,6 cases were underwent CT,and 11 cases were underwent MRI. Results Of the 12 cases with spine EG,there were solitary(10 patients)and multiple lesions(2 patients),totally 15 lesions were found. 15 spine EG lesions in-cluded 2 cervical vertebrae,8 thoraeic vertebraeand 8 lumbar bertebrae. All spine EG lesions were in vertebral bodies,of those, 2 lesions involved into appendages. DR demonstrated flatten vertebrae in different degree with normal or enlarged intervertebral space. CT showed destruction of bone with surrounding osteosclerosis partially. 12 cases examined by MR showed abnormality in the shape and signal of bone. The lesions carried slightly hypointense on T1 WI and hyperintense on T2 WI. 15 cases lesions presented as flattened vertebra or disk change. 3 cases showed soft tissue swelling around the vertebrae and there were the same signal characteristics between the vertebrae and soft tissue. 2 of them oppressed the dural sac and spinal cord. 3 of them presen-ted as kyphosis deformity,and the internertebral disc was normal. Of the 4 patients had Gd-DTPA enhanced MRI,different de-grees of enhancement could be assessed. Conclusion The characteristic imaging features can be seen in spine eosinophilic granuloma in children,the most accurate diagnosis values cand be obtained by MRI,it can be a reliable imageology evidence for clinical diagnosis and treatment.