Effect of alkaline isotonic saline irrigation used in patients after nasal endoscopy for chronic sinusitis

CHEN Qianhong; CHEN Afu; SHENG Lina; XU Yu; WU Yingping; ZHUANG Liping

Abstract：Objective:To explore the effect of alkaline isotonic saline irrigation in patients after nasal endoscopy for chronic sinusitis.Methods:A total of 95 sinusitis patients who underwent endoscopic sinus surgery between April and October 2022 were 2023,according to the chaos table method divided into control group(n=47)and observation group(n=48).The control group patients after postoperative saline irrigation,observation group were given alkaline isotonic saline irrigation after surgery.Postoperative recovery,nasal function[nasal volume(NCV),minimum cross-sectional area(NMCA),nasal airway resistance(NAR),olfactory function score],health quality[nasal and sinus outcomes scale 20(SNOT-20),assessment scale of nasal obstruction symptoms(NOSE),visual analog scale(VAS)],incidence of adverse events were observed in both groups.Results:Compared with the control group,a faster nasal mucosal cilia transmission rate,higher cilia clearance rate,and shorter recovery time of nasal ventilation and nasal mucosa were ob-served in the observation group(P＜0.05).Before surgery,the differences between NCV,NMCA,NAR,olfactory function score and SNOT-20,NOSE,and VAS scores were insignificant(P＞0.05).One month after surgery,NCV and NMCA were significantly higher than the observation group,and NAR,olfactory function,SNOT-20,NOSE and VAS scores were significantly lower than the control group(P＜0.05).The incidence of adverse events of 4.17％in the observation group and 6.38％in the control group was insignificant(P＞0.05).Conclusion:Compared with normal saline nasal irrigation,the use of alkaline isotonic saline is more obvious on the postoperative recovery,nasal function and health quality of patients after chronic sinusitis,and has good safety.