Effect of multi-disciplinary nutrition management on skeletal muscle index loss and radiotherapy course in patients with esophageal cancer

WANG Jingdan; WANG Lulu; WEI Xiaohui

Abstract：Objective:To investigate the effects of multi-disciplinary nutrition management on skeletal muscle in-dex loss and radiotherapy course in patients with esophageal cancer.Methods:A total of 80 patients treated with radio-therapy for esophageal cancer in hospital from January 2020 to January 2023 were selected and divided into study group and control group by simple random method using random number table.40 cases in each group.The control group was given the routine diet intervention program,the observation group was given the whole course of multi-disciplinary nutritional management intervention program.Follow-up was conducted until 6 months after radiotherapy.Nutritional indexes body mass index(BMI),serum albumin(ALB),prealbumin(PAB),skeletal muscle index(SMI)at admission and follow-up,delay time of each radiotherapy period were compared between the two groups at admission and 7 days after inter-vention,and adverse reactions were compared between the two groups at 6 months after radiotherapy.Results:There were no significant differences in various nutrition indexes between the two groups at admission(P＞0.05).Weight after 7 days of in-tervention had no significant change compared with admission(P＞0.05).ALB 7 days after invervention in both groups was lower than that at admission(P＜0.05),the study group was significantly higher than that at admission(P＜0.05).PAB 7 days after invervention in the control group was lower than that at admission,and that in the study group was higher than that at admission.The study group was significantly higher than the control group(P＜0.05).At follow up,the weight of both groups was lower than that at dimission,and in the study group was lower than that in the con-trol group(P＜0.05).The delay time of T0,T1 and T2 radiotherapy in the study group was shorter than that in the control group(P＜0.05).Conclusion:Multi-disciplinary nutrition management can significantly improve the nutrition-al status of patients with esophageal cancer and reduce the loss of skeletal muscle index,so as to ensure the smooth im-plementation of radiotherapy.