Analysis of coagulation function in 112 patients bitten by poisonous snakes in Fenyi County of Jiangxi Province

ZHONG ChunLan; LONG Zhibing; LAN Lijuan

Abstract：Objective:To Investigate the changes of coagulation function in patients bitten by venomous snake.Methods:A total of 112 cases of snakebite patients admitted to the People's Hospital of Fenyi County in Jiangxi Prov-ince from March 2018 to July 2023 were selected as the study subjects,including 56 cases of Russell's viper,28 cases of bamboo pit viper,16 cases of Chinese green tree viper,and 12 of cobra.The results of coagulation function test in differ-ent kinds of patients were compared and analyzed.Results:The three period indexes of different snakes were analyzed by F variance respectively,it was found that only the bamboo leaf green snake group had statistical significance before and after treatment(P＜0.05),and the coagulation function indexes of pit viper,silver snake and cobra groups had no statistical significance(P＞0.05).Then the t test was carried out by pairwise comparison of the three stages of the group.The results showed that the prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),D-dimer(DDi)and fibrinogen(Fbg)of the patients with bamboo snake bite were abnormal before treat-ment,and the indexes were significantly improved after treatment,with statistical significance(P＜0.05).Conclusion:Patients bitten by bamboo green snake can cause serious coagulation dysfunction.