Serum indoleamine 2,3 dioxygenase in children with Kawasaki disease
SHEN Jie
ZHANG Yiying
JIE Chunhong
GONG Fangqi
Abstract：Objective:To detect the level of IDO in patients with Kawasaki disease and analyze correlation between IDO and Kawasaki disease.Methods:Selected 20 cases of KD hospitalized in January 2015 to March 2015 and 20 cases of healthy volunteers.Enzyme-linked immunosorbent assay (ELISA) was adopted to detect the serum levels of IDO.The detection results of all those cases were compared and analyzed.Results:The serum IDO level of the acute phase KD group was significantly higher than that of both the normal control group and the recovery phase KD group(P<0.01).There is no significant difference of IDO level between the recovery phase KD group and the normal control group(P>0.05).There is also no significant gender difference of IDO level among all those groups(P>0.05).Conclusion:The serum IDO level increased in the acute phase KD patients.It might was involved in the acute immune reaction of KD.The IDO level might was not affected by gender.
Keywords：kawasaki diseaseindoleamine 23 dioxygenaseenzyme linked immunosorbent assay
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 253-255 )