Efficacy of domperidone suspension combined with omeprazole in the treatment of infantile pneumo-nia complicated with gastroesophageal reflux disease

YUAN Bo

Abstract：Objective:To investigate the effect of domperidone suspension combined with omeprazole on infants with pneu-monia complicated with gastroesophageal reflux disease. Methods:From January 2012 to January 2016 in hospital,the choice of infant pneumonia complicated with gastroesophageal reflux disease in 60 cases as the research object,all patients were random-ly divided into treatment group(n=30)and normal group(n=30),combined with domperidone suspension group were given routine treatment with omeprazole,the treatment group was treated with domperidone suspension. Treatment effects of two groups were compared. Results:The total effective rate of the treatment group was 93. 3% and 70. 0% in the control group was significantly higher than that in the control group(P﹤0. 05),the difference was statistically significant. The symptom score of gastroesophageal reflux disease(3. 2 ± 0. 5)in the combined group was not different from that in the conventional group(3. 3 ±0.4),andthedifferencewasnotstatisticallysignificant(P﹥0.05).Thesymptomscore(1.2±0.7)inthetreatmentof gastroesophageal reflux disease in the combined group was significantly lower than that in the conventional group(2. 8 ± 0. 7), and the difference was statistically significant(P﹤0. 05). Conclusion:Domperidone suspension and omeprazole can effectively improve the therapeutic effect in children with pneumonia,improve the symptoms of gastroesophageal reflux disease.