Distribution and the drug resistance of 504 pseudomonas aeruginosa isolates

WANG Ruixue; YANG Yun; HE Shaolong

Abstract：Objective:To investigate the distribution and the drug resistance of the P. aeruginosa which isolated from dif-ferent sites of infection and different clinical department. Methods:Collect 504 P. aeruginosa isolates from the hospitalized pa-tients,the antibiotic suscepitibility testing was performed with K-B method then the results were statistically analyzed by the software WHONET 5. 6. Results:The P. aeruginosa strains were mainly isolated from the lower respiratory specimen(75. 2﹪), most of them were obtained from the patients of ICU,neurology department,respiratory medicine department and neurosurgery department. Cefoperazone /sulbactam and imipenem performed a higher drug resistance. The differences of the drug resistance of P. aeruginosa strains which isolated from different sites of infection and different clinical departments were statistically sig-inificance(P﹤0. 05). Conclution:The key departments for the hospital infection control still were ICU,neurology department, respiratory medicine department and neurosurgery department. It is necessary to enhance the management of the use of cefoper-azone /sulbactam and imipenem as well as to monitor the drug resistance of the P. aeruginosa strains so as to reduce the grow-ing of the drug-resistance strains.