Clinical effects for the patients with child idiopathic thrombocytopenic purpura by different doses of gamma globulin combined hormone therapy

HE Weihua

Abstract：Objective:To explore the clinical effects for the patients with child idiopathic thrombocytopenic purpura by different doses of gamma globulin combined hormone therapy. Methods:All 93 cases of patients with child idiopathic thrombo-cytopenic purpura were randomly divided into experiment group A,experiment group B and control group,the control group were treated by carbazochrome salicylate,vitamin K1,dexamethasone,prednisone. On the basis of the control group,the experi-ment group A were treated by high dose immunoglobulin,the control group were treated by low dose immunoglobulin,the plate-let began to rise time,platelet rose to normal time,therapeutic effect and complications were observed. Results:There had no significant difference on the platelet began to rise time,platelet rose to normal time for the experiment group A and experiment group B(P﹥0. 05). The platelet began to rise time,platelet rose to normal time for the experiment group A and experiment group B were lower than the control group(P﹤0. 05). There had no significant difference on the clinical effects for the experi-ment group A and experiment group B(P﹥0. 05). The clinical effects for the experiment group A and experiment group B were higher than the control group(P﹤0. 05). The rate of complication for the experiment group A were higher than the experiment group B and control group(P﹤0. 05). The rate of complication for the experiment group B was same as the control group(P﹥0. 05). Conclusion:It has clinical curative effect quite for the patients with child idiopathic thrombocytopenic purpura by differ-ent doses of gamma globulin combined hormone therapy,it can reduce the platelet began to rise time,platelet rose to normal time,it has low rate of complication with low dose immunoglobulin,it has high values of clinical application.