The relationship between serum homocysteine level and the efficacy of rt-PA intravenous thrombol-ysis in young patients with acute cerebral infarction
SUN Tingting
ZHANG Peilan
Abstract：Objective:To investigate the relationship between serum homocysteine( HCY)level and the efficacy of recom-binant human tissue-type plasiminogen,actilyse( rt-PA)intravenous thrombolysis in young patients with acute cerebral in-farction. Methods:Retrospective analysis was performed in 382 patients with young acute cerebral infarction treated with rt-PA intravenous thrombolysis in the department of internal medicine in tianjin huanhu hospital from June 2014 to June 2015. The serum HCY level of normal patients in 156 cases,226 cases of patients with elevated serum HCY. The two groups of patients were recorded before treatment,after treatment 24 h and 7 d national institute of health stroke scale( NHISS)score,before treatment,after treatment 30 d and 90 d modified rankin scale( mRS)score. Analysis of the relationship between serum HCY level and prognosis of patients with acute cerebral infarction treated with rt-PA intravenous thrombolysis. Results:The NIHSS score and mRS score after treatment in the patients with elevated serum HCY were higher than those in the normal group of ser-um HCY. Conclusion:The increase of serum homocysteine is one of the factors that affect the prognosis of patients with acute cerebral infarction in young patients with acute cerebral infarction rt-PA.
Keywords：homocysteineyouth cerebral infarctionintravenous thrombolysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 5-7 )