Clinical significance of serum pepsinogen detected in the diseases of the stomach
LIANG Yanli
LI Feng
WANG Xin
PU Zeyan
Abstract：Objective:To explore the clinical significance of serum pepsinogen I(PGI)and pepsinⅡ(PGⅡ)concentration and PGI/ PGⅡ ratio(PGR)in gastric cancer,gastriculcer and chronic superficial gastritis. Methods:The serum concentations of PGI and PGⅡ were detected with time - resolved fluorescence immunoassay,and calculated the ratio. Results:Gastric cancer is compared to gastric ulcer,chronic superficial gastritis and the control group,significantly lower about serum PGI and PGR lev-el;PGⅡin Gastric cancer,gastric ulcer and chronic superficial gastritis is higher than the control group. In terms of PGI and PG Ⅱ positive detection rate,gastric cancer group showed the highest. Conclusion:The determination of serum PGI,PG Ⅱ and PGR for diagnosis and identification of stomach disease has certain clinical significance,especially the clinical screening of the gastric cancer improve the early diagnostic rate.
Keywords：pepsinogengastric cancergastriculcerchonic superficial gastritis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 594-596 )