The investigation on genetic polymorphisms of 19 STR loci in Han population in Gaoping of Shanxi
LIU Yanjun
HE Xiaohua
GONG Zhigang
LI Lin
WANG Bing
ZHANG Tianlin
Abstract：Objective:To study the genetic polymorphisms of short tandem repeats(STR)loci in Han population in Gaop-ing of Shanxi province,and evaluate their forensic application. Methods:Nineteen STR loci including D19S433 were amplified by using a Goldeneye 20A STR Amplification Kit,and analyzed by 3130XL genetic analyzer. 210 unrelated individuals of Han population in Gaoping city of Shanxi province were investigated to obtain the allele frequencies and forensic genetics data. Re-sults:Allele distributions of the 19 STR loci have been obtained. 10,9,15,13,13,6,8,7,7,7,10,8,9,5,17,6,11,13 and 17 alleles were found in the preview 19 STR loci. We also obtained some parameter of forensic genetics respectively,such as het-erozygosit(Ho),expected heterozygosity(He),discrimination power(DP),matching probability(PM),probability of paternity exclusion(PE)and polymorphism information content( PIC). The cumulative discrimination power( CDP)and cumulative probability of exclusion(CPE)of 19 loci is 1 ~ 1. 49 × 10 - 22 and 0. 999 999 993. Conclusion:The 19 STR loci are highly poly-morphic and suitable for forensic personal identification and paternity testing in Gaoping city of Shanxi province. There are sig-nificant value in the application of forensic personal identification and paternity testing.
Keywords：forensic geneticsgenetic polymorphismshort tandem repeatsgene locusGaoping Han population of Shanxi
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 535-539 )