The clinical application of procalcitonin and endotoxin limulus in community - acquired pneumonia of children

WANG Ping; WANG Huabin; LUO Kaiyuan

Abstract：Objective:To evaluate the clinical diagnostic value of procalcitonin(PCT)combined with endotoxin Limulus test in children community - acquired pneumonia. Methods:From January 2014 to December 2015,admissions 120 cases of community - acquired pneumonia in children,according to etiology findings will be divided into groups of bacteria and non -bacterial group,the group of children with bacterial subdivided into Gram - negative bacteria infection group(A group)and non - Gram - negative bacteria infection group(group B),all children with procalcitonin,quantitative determination of endo-toxin limulus test,observe the test results. Results:According to test results can be seen in children with positive rates of bacte-rial infection procalcitonin group was higher than that of children of non - bacterial group,the comparison of the data between the two groups of children was significantly(P ﹤ 0. 05),with statistical significance. Endotoxin by the Limulus test,found that children with serum toxin A group changed significantly in the serum group B toxin no significant change,data comparison be-tween the two groups of children was significantly(P ﹤ 0. 05),with statistical significance. Conclusion:Serum procalcitonin for early diagnosis of children with community - acquired pneumonia have greater clinical value,quantitative LAL endotoxin assay can determine the type of bacteria,to prevent the wrong use of antibiotics,due to the direction of reducing medication errors ef-fective treatment for clinical medicine has important reference value.