Clinical characteristics of frequent peritoneal dialysis related peritonitis

LI Xiaoli; LI Qian; ZHANG Qingjuan; YUAN Zijing; ZHU Jiang

Abstract：Objective:To identify the clinical characteristics,and explore the cause of frequent peritoneal dialysis related peritonitis. Methods:A retrospective analysis was conducted in the peritonitis patients undergoing peritoneal dialysis in our hos-pital. Frequent peritoneal dialysis related peritonitis was defined by two or more onsets in one year,and the patients with only one onset served as the control group. The clinical and laboratory data of the two groups were compared and the cause of perito-neal dialysis related peritonitis analyzed. Results:No significant differences were found between the two groups in age,gender, culture degree ,incidence of diabetes mellitus ,serum creatinine ,calcium ,phosphorus ,potassium and blood leucocytes( P ﹥0 . 0 5 ). There were significant differences in serum albumin level at the start of peritoneal dialysis therapy and at peritonitis between two groups . The infection rate of gram - positive bacteria in frequent group was higher than the sporadic group( P =0. 034),the infection rate of gram-negative bacteria is slightly lower than the sporadic group(P=0. 038),no other signifi-cant difference in bacterial spectrum. Logistic regression analysis shows that there was positive correlation between serum albu-min level at the start of peritoneal dialysis therapy and peritonitis episodes(OR= -1. 124,P=0. 001). Conclusion:Hypoalbu-minemia may be one liability factor of frequent peritoneal dialysis related peritonitis. Measures to ameliorate hypoalbuminemia early may help prevent and control frequent peritoneal dialysis related peritonitis.