Drug sensitivity comparison between BACTEC - MGIT 960 and Roche proportion
YANG Shun-li
BU Hong-li
FAN Meng-bai
Abstract：Objective:To compare the consistency of the method for the detection of the fast drug sensitivity of BACTEC -MGIT960 and the ratio of Roche to the drug sensitivity test. Methods:Parallel detection of the hospitalized patients with Myco-bacterium tuberculosis drug sensitivity of separated strains 245 strains of rifampicin( RFP),isoniazid( INH),streptomycin (SM)and ethambutol(EMB). Results:By contrast detection,BACT - MGIT960 automatic mycobacteria drug sensitivity deter-mination can inspect the drug sensitivity of RFP,INH,SM,EMB in the 4 ~ 13 d and average 7. 8 days. The coincidence rate of drug sensitivity was 98. 78% ,97. 55% ,96. 73% ,96. 73% ,respectively. The average coincidence rate was 97. 45% ,and the correlation was 97. 5% . Conclusion:BACTEC - MGIT 960 liquid drug sensitive system,can quickly and accurately obtain drug sensitivity test results,especially for clinical isolates of rapid drug sensitive screening.
Keywords：MGIT960 systemDrug sensitivity testproportion methodmycobacterium tuberculosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 919-921 )