To investigate the efficacy and safety of stenting and drug therapy alone in treating patients with vertebral artery stenosis

TANG Zhao; OUYANG Shen; YANG Guo-dong

Abstract：Objective:To investigate the efficacy and safety of stenting combine with drug and drug therapy alone in trea-ting patients with vertebral artery stenosis. Methods:A retrospective analysis of 74 patients with moderate to severe vertebral ar-tery beginning part stenosis from February 2012 to June 2014,according to their treatment,divided into the stent group and the drug group,38 stent group patients taken stents and drug treatment,36 drug group cases treated with drug therapy alone,com-pared the difference between the two groups patients in general,clinical efficacy and safety. Result:There were no statistically significant differences in the age,sex,and other risk factors for cerebrovascular such general aspects of two groups patients(P﹥ 0. 05);the average postoperative residual stenosis of stent group patients was(7. 3 ± 3. 8)% ,national Institute of Health stroke scale(NIHSS)score after surgery being(2. 3 ± 0. 9),followed up six cases of ischemic events a year(15. 8% ),6 cases restenosis(15. 8% )compared with the drug group with the mean residual stenosis rate being(53. 2 ± 10. 1)% ,NIHSS score after surgery being(3. 7 ± 1. 1),1 - year follow - up of 14 cases of ischemic events(38. 9% ),restenosis 13 cases(36. 1% ) with a significant difference(P ﹤ 0. 05). Conclusion:Stenting with drug in treating patients with vertebral artery stenosis has a more satisfactory clinical efficacy,while with higher security,worthy of clinical application.