Study on the structure of fat emulsion effect on resting energy metabolism and lipid peroxidation in patients with gastrointestinal cancer

TANG Cheng; CAO Chao; RUAN Li-qin

Abstract：Objective:To study the structure of fat emulsion(C6 - 24 Li Wen)effect on resting energy metabolism and lipid peroxidation in patients with gastrointestinal cancer. Methods:From 2013 July to 2014 July 82 patients with gastrointesti-nal tumor treated in hospital,which were randomly divided into structure of fat emulsion(STG)group and medium and long chain triglyceride emulsion(MCT/ LCT)group,two groups each of 41 patients. Patients in the postoperative 2 ~ 6 days respec-tively by STG and MCT/ LCT etc. constituten,heat PN support,5 d. Results:after an operation group 6 d STG of gastrointestinal tumor patients accumulated nitrogen balance value and the MCT/ LCT group of gastrointestinal tumor patients compared to the lower(P < 0. 05). The level of 4 d hypersensitive C - reactive protein(hs - CRP)and MCT/ LCT groups were compared with low STG group of gastrointestinal tumor patients first ~ after operation(P < 0. 05). Serum Malondialdehyde(MDA)in the pa-tients with gastrointestinal tumor concentration of STG group was lower than that of group MCT/ LCT patients of gastrointestinal tumor,statistically significant data difference(P < 0. 05),STG group of gastrointestinal cancer patients and the level of gluta-thione peroxidase(GSH - Px)was higher than group MCT/ LCT patients of gastrointestinal tumor,statistically significant data difference(P < 0. 05). Conclusion:STG group of gastrointestinal tumor patients using PN to support smaller metabolic disor-ders caused by the treatment of gastrointestinal tumor patients,in terms of reducing lipid peroxidation damage and maintain the stability of energy metabolism,STG better than MCT/ LCT.