The application of pituitrin in laparoscopic myomectomy

HUO Qiao-ling; REN Su-fang; LI Ying; HAN Xiu-qing; LIU Cai-qing; LIU Zhi-xian

Abstract：Objective:To evaluate the efficiency and safety of different doses pituitrin in patients undergoing laparoscopic hysteromyomectomy. Methods:Using the method of random number table,ninety patients who scheduled for elective laparoscop-ic myomectomy under general anesthesia,were divided into three groups(n = 30 each):control group(group C)and different doses pituitrin groups(group P1 and group P2). Group P1 was given myometrium injection with pituitrin 6 U,group P2 was giv-en myometrium injection with pituitrin 12 U,and group C was given oxytocin 20 U. To observe the operation situation,intraop-erative complications and postoperative recovery of three groups,and then compare the clinical efficacy of three groups. Re-sults:The operation time of group P1 and P2 was significantly shorter as compared with the group C,the intraoperative blood losswas less than that of the group C( P ﹤ 0 . 0 5 ). The incidences of cardiovascular responses were 6 . 6 7 % ,4 6 . 6 7 % and 96. 67% in group C,P1 and P2 respectively. The incidence of cardiovascular responses in group P1 and group P2 was signifi-cantly higher as compared with group C(P ﹤ 0. 01,correction αˊ= 0. 0167). The incidence of cardiovascular responses was sig-nificantly higher in groups P2 than in group P1(P ﹤ 0. 01). There were no serious complications in three groups postoperative. Conclusion:Small dosage pituitrin can effectively reduce the intraoperative blood loss and shorten the operation time with few complications in patients undergoing laparoscopic hysteromyomectomy.