Mild chronic kidney disease independently predicts adverse outcomes in women with symptoms and signs of ischemia
ZHANG Tao
WANG Song-tao
LIU Yue-hong
Abstract：Objective:To investigate mild chronic kidney disease( CKD)independently predicts adverse outcomes in women with symptoms and signs of ischemia. Methods:To categorize 269 women referred for clinically indicated coronary angi-ography according to estimated glomerular filtration rate(eGFR). Time to death from all - cause and cardiovascular causes and major adverse outcomes were assessed by multivariate regression adjusted for baseline covariates. Results:Obstructive coronary artery disease(CAD)was present only in few patients(41% ). Even after adjusting for CAD severity,renal function remained a strong independent predictor of all - cause and cardiac mortality(P ﹤ 0. 001). Every 10 - unit decrease in eGFR was associ-ated with a 13% increased risk of all - cause mortality,17% increased risk of cardiovascular mortality,and 8% increased risk of adverse cardiovascular events. Conclusion:Even mild CKD is a strong independent predictor of all - cause and cardiac mor-tality in women with symptoms/ signs of ischemia.
Keywords：glomerular filtration ratecoronary artery disease severity scorechronic kidney diseaseall - cause mortality
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 645-649 )