To evaluate the effect and clinical outcome of interventional therapy for lower limb ischemia

OUYANG Xin; KANG You-gen; HU Zan; FANG Zhi-hong; LI Wen-quan; ZENG Yin; MO Shu-zhen; LI Dan

Abstract：Objective:To evaluate the effect and clinical outcome of interventional therapy for lower limb ischemia. Meth-ods:Data of 260 patients with lower limb ischemia confirmed by vascular ultrasoundand and 64 - slice spiral computed tomo-graphy angiography(CTA). Among all patients,65 limbs were iliac arterial occlusion,and 202 case were iliac and femoral arte-rial,58 cases were femoral - popliteral and infra - popliteral artery,43 cases were infra - popliteral artery. All arteries under-went percutaneous transluminal angioplasty(PTA)and selected stent implantation fellowed in cases of dissection or residual stenosis after balloon angioplasty(179 patients,203 stents). All patients were followed up for 12 ~ 72 months. The middle and long - term efficacy after interventional therapy was analyzed. Results:NO severe complications such as angiorrhexis and perfo-ration were found during the interventional therapy. The symptoms of lower limb ischemia of all patients after interventional therapy were alleviated or disapp - eared. During the follow - up,3 patients died of acute myocardial infarction or strike at 16 months after interventional the - rapy,and 142 patients had the symptoms of lower limb ischemia again. DSA showed that stent occlusion caused by intimal hyperplasia occurred in 80 cases,and lower limb ischemia caused by vascular lesions at the site of non - therapy occurred in 30 cases,and the restenosis at the site of th - rombolysis and PTA therapy were 9 cases. These pa-tients got better and discharged from the hospital after PTA or stent implantation therapy. The other 115 cases had no recur-rence. The result of vascular ultrasound re - examinaxion showed smooth lumens and good blood flow. Conclusion:Int ervention-al therapy for lower limb ischemia has minimal invasion and good middle and long - term efficacy,so it has value of clinical ap-plication.