Study on the influence of general anesthesia and epidural anesthesia on cognitive function of elderly patients after total hip replacement
YANG Yan
WANG Zhong-sheng
Abstract：Objective:To investigate the influence of general anesthesia and epidural anesthesia on cognitive function of elderly patients after total hip replacement. Methods:Sixty - eight cases of elderly patients undergoing total hip replacement were randomly divided into two groups,the control group was treated by tracheal intubation general anesthesia,the observation group was treated by continuous epidural anesthesia. To evaluate the cognitive function before and after anesthesia using mini mental state examination scale(MMSE). Results:The MMSE scores of patients in the control group after anesthesia,6 h,12 h and 24 h were significantly lower than before the induction of anesthesia,with statistically significant difference(P <0. 05),and the observation group after anesthesia,6 h,12 h and24 h MMSE were lower than those before induction of anesthesia,but the difference was not statistically significant(P >0. 05),compared with the control group with significant difference(P <0. 05). Af-ter 6 h,12 h and 24 h,the incidence of postoperative cognitive dysfunction(POCD)of observation group were 14. 71% ,8. 82%and 5. 88% ,were significantly lower than the control group and the difference had statistical significance(P <0. 05). Conclusion:The effect of epidural anesthesia on POCD in elderly patients with total hip replacement is significantly reduced compared with general anesthesia,has better clinical application value,is suitable for popularization and application.
Keywords：general anesthesiaepidural anesthesiatotal hiparthroplastycognitive function
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 338-340 )