Clinical efficacy observation of atorvastatin in the prevention and treatment of acute ischemic stroke

HUANG Wei-hua

Abstract：Objective:To observe the application and clinical efficacy of atorvastatin in the prevention and treatment of a-cute chemist stroke. Methods:From October 2011 to October 2013,86 patients with acute ischemic stroke were admitted and divided into control group and observation group,43 cases in each group,all cases in control group were treated oral entertainer—coated aspirin(100 mg/d,one times one day)and other basic treatment;all cases in observation group were treated with atorvastatin(20 mg/d,one times one day,30 d was a period of treatment in two groups. To compare the clinical effect of two group. Results:The total effective rate was 72. 1%(31/43)in control group,the level of blood fat significantly improved after treatment,acute cerebral infarction in two cases,gastrointestinal reactions in three cases,liver dysfunction in two cases,the rate of adverse reactions was 16. 3%. The total effective rate was 88. 4%(38/43)in observation group,the level of blood fat sig-nificantly improved after treatment,acute cerebral infarction in one case,gastrointestinal reactions in two cases,liver dysfunc-tion in one case,the rate of adverse reactions was 9. 3%. The total effective rate was statistically significant(P<0. 05)be-tween two group. Conclusion:In the clinical course of patients with acute chemist stroke,the treatment effect of atorvastatin is significant,adverse reactions is little,the prognosis is good.