The Study on the Intervention Effect of High Dietary Fiber and Low GI Coarse Grain Food for Pre- diabetic Patients' Gut Microbiota
AN Yang
ZHANG Wen-qing
GUO Li-na
LIU Juan
HAO Dan-dan
Abstract：Objective:To analyze the intervention effect of high dietary fiber and low GI coarse grain food for pre - diabet-ic patients' gut microbiota. Methods:100 pre - diabetic patients were selected from the community,and randomly divided into intervention group and control group. There were 50 people in each group. The intervention group was intervened for two months with nutrition formulation food(soluble dietary fiber and low - GI coarse grain),combined with nutrition education,exercise in-tervention,diet intervention,psychological interventions and other medical nutrition intervention measures. The control group had no measures. Comparing the difference in the two groups,gut microbiota(lactobacillus,bifidobacteria,E. coli)using fluoro-genic quantitative PCR before and after the intervention. Results:After the intervention,the intervention group's lactobacillus and bifidobacteria increased obviously(P ﹤ 0. 05),and E. coli declined obviously(P ﹤ 0. 05). The control group's indicators had no change(P ﹥ 0. 05). Conclusion:The high dietary fiber and low GI coarse grain food can adjust the structure of gut mi-crobiota of pre - diabetic patients,support beneficial intestinal bacteria,suppress conditioned pathogen,restore intestinal micro-flora,and prevent or delay the occurrence and development of chronic metabolic disease.
Keywords：pre - diabetesgut microbiotadietary fiberlow GI coarse grain
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 163-166 )