The expression of IL-17 and CXCL10 in the blood of patients with type 1 diabetes and its clinical significance
WANG Liang
LI Hong-ling
LIU An-ning
HUANG Jing
ZOU Yi
ZHANG Gao-sheng
Abstract：Objective:ToinvestigatetheexpressionofIL-17andCXCL10inpatientswithtype1diabetesMellitusand its clinical significance. Methods:Double antibody sandwich enzyMe-linked iMMunosorbent assay( ELISA),was used to de-tect the expression levels of IL-17 and CXCL10 in seruM of 30 patients with type 1 diabetes and 20 cases of healthy children ( control group). Results:The expression levels of IL-17 and CXCL10 in seruM in patients with type 1 diabetes were signifi-cantly higher than those in norMal control group,the difference has statistical significance(P﹤0. 05). Conclusion:In patients with type 1 diabetes,the expression levels'increase of IL-17 and CXCL10 in seruM May contribute to the occurrence of islet inflaMMation and type 1 diabetes.
Keywords：IL-17CXCL10Type1diabetes
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 107-109 )