Efficacy and impact on fetus of antithyroid drugs on pregnant women with hyperthyroidism

SHI Wei; QIU Chang-lian

Abstract：Objective:To investigate the efficacy of antithyroid drugs on pregnant woMen with hyperthyroidisM and the iM-pact on fetus. Methods:96 cases of pregnant woMen with hyperthyroidisM in our hospital froM May 2009 to May 2014 were se-lected and randoMly divided into control group and observation group,each group 48 cases. Patients in control group were not adMinistrated with anti - thyroid drugs,and patients in observation group were dealed with antithyroid drugs. The thyroid func-tion,the pregnant woMen coMplications,the newborn average weight and the one Minute Apgar scores of two groups were ana-lyzed and coMpared. Results:The FT3,FT4 and TSH levels of observation group were significantly lower than control group(P﹤ 0. 05). The pregnant woMen coMplications rate of observation group was significantly lower than control group(P ﹤ 0. 05). The newborn average weight of observation group was significantly higher than control group,and the Apgar score high of obser-vation group was significantly higher than control group. The differences were statistically significant(P ﹤ 0. 05). Conclusion:For pregnant woMen with hyperthyroidisM,antithyroid drugs can significantly iMprove thyroid function,the newborn average weight and one Minute Apgar scores.