Analysis of risk factors for pancreatic fistula of patients with pancreatic trauma

GUO Wen-ke; JIA Bin; YAN Hui-ming; SHEN Su-gang

Abstract：Objective:To discusse the risk factors of pancreatic fistula after operative management of pancreatic trauma. Methods:Fifty-nine patients of pancreatic trauma received operative management in the second clinical hospital of shanxi medical university. from March 2000 to November 2003 was analyzed. Eight single risk factors for pancreatic fistula of perioper-ative period were univariate analyzed,and the independent risk factors for pancreatic fistula of perioperative period were screened and included in a multivariate Logistic regression for analysis. Results:All of the 59 patients,the pancreatic fistula was 24(40. 7%),and pancreatic external fistula occurred in18 of patients,and pancreatic pseudocyst occurred in 6 patients, single factor analysis showed that,the time between injury and operative,and increased value of amylase of fluid drainage,and the degree of pancreas injury was significantly different between two group. The above three of factors have been introduced into the multiple factors Logistic models which shows that the time between injury and operative≥12 h(OR=6. 654),the degree of pancreas injury exceeding classⅢ(OR= 8. 393),increased value of amylase of fluid drainage(OR=12. 883)were independ-ent risk factors for pancreatic fistula. Conclusion:the time between injury and operative≥12 h,the degree of pancreas injury exceeding classⅢ,increased value of amylase of fluid drainage predict a high probability of pancreatic fistula after operative management of pancreatic trauma.