The effect observation on berberine hydrochloride tablets combined quadruple chemotherapy for the eradication of helicobacter pylori
LIU Xiao-hua
XUE Lin-long
Abstract：Tocomparetheclinicaleffectofberberinehydrochloridetabletscombinedquadruplechemotherapy for the eradication of helicobacter pylori( Hp),provide reference for the choice of treatment. Methods:A total of 160 patients with helicobacter pylori positive peptic ulcer disease were dvided into two groups . The group A :take orally esomeprazole (20 mg)+amoxicillin(1. 0 g)+colloidal bismuth subcitrate(220 mg)+ clarithromycin(0. 5 g),2 times per day,for ten days. The group B:take orally esomeprazole(20 mg)+colloidal bismuth subcitrate(220 mg)+amoxicillin(1. 0 g)+clarithro-mycin(0. 5 g),2 times per day,+berberine hydrochloride tablets(300 mg),3 times per day,for ten days. To observe and re-cord the eradication and adverse reactions of Hp. Results:The total eradication rate of HP of the group A were 81. 23%. The total eradication rate of HP of the group B were 87. 50%,siginificantly higher than the group A,the difference was statistically siginifiant(P﹤0. 05). The incidence adverse reactions of group B and group A were simler. The difference was not statistically siginificant(P﹥0. 05). Conclusion:Bismuth agent four transmitte adverse reactions did not significantly increased,the eradica-tion rate is higher,is the ideal reatment.
Keywords：helicobacterpylorieradicationrateeffectobservation
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 576-577,578 )