Relationship between latent profiles of symptom characteristics and supportive care needs in postoperative breast cancer patients undergoing chemotherapy
ZHAO Xiaohan
LI Ping
HOU Ming
DU Guangping
ZHUANG Tianqing
CHEN Haoyu
Abstract：Objective:To analyze the latent profiles and influencing factors of symptom characteristics in postoperative breast cancer patients undergoing chemotherapy,and to explore the relationship between different symptom profiles and supportive care needs.Methods:A total of 302 postoperative breast cancer patients receiving chemotherapy from November 2023 to August 2024 were selected from three tertiary Grade A hospitals in the Xinjiang Uygur Autonomous Region.A general information questionnaire,the Memorial Symptom Assessment Scale,and the 34-item Short-Form Supportive Care Needs Survey were used for investigation.Latent profile analysis was employed to identify potential profiles of symptom characteristics.Univariate analysis and multinomial logistic regression were used to analyze the influencing factors of different profiles and their relationship with supportive care needs.Results:The symptom characteristics of postoperative breast cancer patients undergoing chemotherapy could be categorized into three latent profiles:a low-symptom burden group(54.3%),a moderate-symptom burden-gastrointestinal symptoms group(28.5%),and a high-symptom burden group(17.2%).Body Mass Index(BMI),number of comorbidities,number of chemotherapy cycles,and whether targeted therapy was used,psychological needs,care and support needs were identified as influencing factors for the symptom characteristics across different profiles(P<0.05).Scores on physiological and daily living needs,psychological needs,and care and support needs significantly differed among the different profile groups(P<0.05).Conclusions:Symptoms among postoperative breast cancer patients undergoing chemotherapy demonstrate significant population heterogeneity and are associated with varying levels of unmet supportive care needs.Nursing staff should implement patient-centered symptom management strategies based on patients' specific symptom profile characteristics to meet their supportive care needs effectively.
Keywords：breast cancersymptom burdensupportive carecare needslatent profile analysissurvey research
Publication Date：2026-03-10
Online Publishing Date：2026-03-16(First online date of this platform, not the publication date of the document)
Pages：8( 828-835 )