Best evidence summary for the assessment and management of patients with sepsis-associated brain dysfunction
HE Hua
WANG Lili
ZHANG Ling
LI Na
SUN Xun
CHAI Chao
WANG Dan
CHENG Lin
Abstract：Objective:To summarize the best evidence for the assessment and management of patients with sepsis-associated brain dysfunction(SABD).Methods:Literature related to the assessment and management of SABD patients were retrieved from domestic and international databases.Literature types included clinical decision-making,evidence summaries,guidelines,systematic reviews,best practices,and expert consensus.The retrieval time spanned from database establishment to July 2,2024.The quality of the literature was evaluated,and data were extracted.Results:A total of 10 articles were included,comprising 2 expert consensus,2 guidelines,and 6 systematic reviews.The overall quality of the included literature was high.Ultimately,12 best evidence statements were summarized across 4 aspects(influencing factors,assessment and differentiation,monitoring and treatment,and rehabilitation and follow-up).Conclusions:The best evidence for the assessment and management of SABD patients summarized in this study demonstrates scientific validity and practical applicability.It could provide a reference for clinical practice.
Keywords：sepsisbrain dysfunctioncognitive impairmentevidence summaryevidence-based nursing
Publication Date：2025-09-25
Online Publishing Date：2025-09-30(First online date of this platform, not the publication date of the document)
Pages：7( 3109-3115 )