Application of stone needle thermo-compress therapy with warm stomach-strengthen spleen ointment in hematopoietic stem cell transplantation patients
YAO Binlian
XU Min
MAO Xiaopei
PENG Min
ZHU Rui
SHEN Wangfang
CHENG Fang
Abstract：Objective:To explore the application effect of bian stone thermo-compress therapy with warm stomach-strengthen spleen ointment in hematopoietic stem cell transplantation(HSCT)patients.Methods:A total of 66 HSCT patients admitted to the hematology department of a tertiary grade A hospital in Hangzhou city were selected as the study subjects from October 2023 to March 2024.The patients were randomly divided into intervention group and control group by using random number table(33 patients each).The control group cases received fosaprepitant dimeglumine for injection and routine care,while the intervention group cases received bian stone thermo-compress therapy with warm stomach-strengthen spleen ointment based on the control group.The incidence of nausea and vomiting,as well as pepsinogen levels were compared between the two groups.Results:The incidence of nausea in the intervention group(63.6%)was lower than that of the control group(87.9%).And the incidence of vomiting in the intervention group(54.5%)was lower than that of the control group(84.8%).There were statistically significant differences between the two group(P<0.05).The grading of nausea showed between-group and time effects(P<0.05).While the grading of vomiting showed between-group and time effect(P<0.05).On the 8th day of preconditioning,the levels of pepsinogen I[(154.70±47.09)μg/L]and pepsinogen Ⅱ[(14.36±4.11)μg/L]in the intervention group were lower than those in the control group[(181.85±53.51)μg/L and(20.00±3.61)μg/L,respectively].Conclusions:Bian stone thermo-compress therapy with warm stomach-strengthen spleen ointment was beneficial for reducing the incidence and severity of nausea and vomiting in HSCT patients.It could also mitigate the impact on pepsinogen levels.
Keywords：bian stonetraditional Chinese medicinemedicinal ironing therapyhematopoietic stem cell transplantationnauseavomiting
Publication Date：2025-07-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 2444-2449 )