Clinical effect of venous-access ports and PICC in patients with tumor chemotherapy:a systematic evaluation
Kong Dehua
Zhang Lei
Chu Jing
Abstract：Objective:To systematically review the clinical effect of venous-access ports(VPA/VAP) and peripheral venous catheterization(PICC) in patients with tumor chemotherapy.Methods:Randomized controlled trial(RCT),semi-randomized controlled trial,and cohort study of comparison the application effect of VAP and PICC in patients with tumor chemotherapy were retrieved from the Cochrane CDSR,PubMed,Embase,CINAHL,SCIE,Chinese biomedical literatures service system (CBM),Wanfang,and VIP database.According to the inclusion criteria,two researchers selected the literature,extracted the data,and evaluated the quality,and conducted a meta-analysis of the outcome indicators by the RevMan5.3 software.Results:A total of 6 RCTs,2 semi-RCTs,and 7 cohort studies involved 2 061 patients were included in this study.The meta-analysis showed that,the incidence of catheter jam [relative risk(RR) =0.26,95 ％ confidence interval(CI) (0.15,0.42),P＜0.05],the incidence of catheter infections [RR =0.23,95 ％ CI (0.14,0.38),P＜0.05],the incidence of phlebitis[RR=0.11,95 ％ CI (0.05,0.25),P＜0.05],the incidence of catheter shift/out [RR=0.18,95％CI(0.09,0.39),P＜0.05) of the experimental group(using VAP) were significant lower than those of the control group,the difference was statistically significant.The average catheter indwelling time[standardized mean difference(SMD) =1.22,95 ％CI(0.38,2.05),P＜0.05] of the experimental group was significantly better than that of the control group,and the difference was statistically significant.There was no statistically significant difference between the two groups in the success rate of the first catheter(P＞0.05).Conclusions:Compared with PICC,VPA had advantages on extending the catheter indwelling time,reducing the incidence of catheter blockage,catheter infection,phlebitis,and catheter shift/out,which was a more safe and effective venous pathway.
Keywords：tumorchemotherapyvenous-access ports(VPA/VAP)peripherally inserted central catheter(PICC)systematic evaluationmeta-analysiscomplications
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 1407-1414 )