Influence of Dioscorea opposita porridge on blood glucose and blood lipid in patients with type 2 diabetes mellitus

doi:10.3969/j.issn.1009-6493.2017.16.008

Abstract：Objective:To observe the influence of Dioscorea opposita porridge on blood glucose and blood lipid in patients with type 2 diabetes mellitus,and to provide a scientific basis for the promotion and application of Dioscorea opposita porridge.Methods: A total of 90 patients with type 2 diabetes mellitus from a grade A tertiary hospital's health education club were randomly divided into experimental group and control group by random number table method,45 cases in each.The patients in control group were given the routine outpatient follow-up and health education,and on the basis,the patients in experimental group were given Dioscorea opposita porridge once a day.That was continuously intervened for 12 weeks.The scores of blood glucose and blood lipid were measured before and after the intervention and were analyzed by per-protocol population(PP) and Intention to treat(ITT) methods.Results: After 12 weeks intervention,the values of fasting blood glucose and blood glucose of postprandial 2 h were analyzed by PP analysis and ITT analysis,the difference was statistically significant(P<0.05).In the blood lipid indexes,PP analysis only showed that the between-group difference value of TG was statistically significant(P<0.05).ITT analysis only showed that the between-group difference value of TC was statistically significant(P<0.05).There was no significant difference between the two groups on other differences(P>0.05).There was no significant difference in the quality of life between the two groups(P>0.05).Conclusions: Dioscorea opposita porridge had the effect for reducing fasting blood glucose and blood glucose of postprandial 2 h in patients with type 2 diabetes mellitus,and the regulation of blood lipid level was still uncertain.During the 12-week intervention,there was no adverse effect on the quality of life of patients with type 2 diabetes mellitus.