Application of mechanical bowel preparation in elective colorectal surgery:a meta-analysis
Abstract：Objective:To systematic review the clinical value of mechanical bowel preparation (MBP)in elective colorectal surgery.Methods:Cochrane systematic review was used to retrieve the data from Cochrane Library, PubMed,Embase,Web of Science and CBM from 2005 to 2015.The quality of literature was independently eval-uated by two evaluators,the indicators for assessment including the rate of anastomotic leak,wound infection and abdominal abscess incidence.The results were analyzed with RevMan 5.3 software.Results:A total of 10 pa-pers were included in the meta-analysis.In experimental group,MBP was performed before elective colorectal surgery.In control group,MBP was not performed before an operation.Meta-analysis showed that there were no statistically significant differences between two groups in the incidence of anastomotic leakage[OR =0.85, 95%CI (0.621.17),P =0.32]and the incidence of wound infection[OR=1.15,95%CI (0.931.42),P =0.18] (P > 0.05 ).There was statistically significant difference in incidence of abdominal abscess between the two groups[OR=0.61,95%CI (0.40 ~0.94),P =0.02].Conclusions:There were insufficient evidences to support that the use of MBP during elective colorectal surgery may reduce anastomotic leakage and wound infection. Further study is needed.
Keywords：mechanical bowel preparation MBPcolorectal surgeryelective surgerysystemic evaluationanasto-motic leakagewound infectionabdominal abscess
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 802-806 )