Distribution of pathogenic bacteria in lower respiratory tract infection and its risk factors in critical ill patients of neurosurgery
Lü Yan
Wang Yan
Xi Xiuming
Abstract：Objective:To probe into the distribution of pathogenic bacteria in lower respiratory tract infection and its risk factors in critical patients of neurosurgery.Methods:A total of 128 traumatic brain injury patients in our hospital receiving diagnosis and treatment of from September 2013 to February 2016 were selected,the occurrence of lower respiratory tract infection was observed and carried out isolation and identification of pathogenic bacteria,analyzed high-risk factors leading to lower respiratory tract infection.Results:There were 28 cases with lower respiratory tract infection in 128 cases,the incidence was 21.9 ％.25 cases of pathogenic bacteria were detected,the detection rate was 89.3 ％.A total of 36 pathogenic microorganisms were detected,including 25 Gram-negative bacteria,Gram-positive bacteria 10,1 fungi.The results of univariate analysis showed:age,use of broad-spectrum antibiotics,body mass index,lymphocyte count,smoking,tracheal intubation,deep vein catheterization had influence on neurosurgical critically ill patients complicated with lower respiratory tract infection(P＜0.05).The logistic multivariate regression analysis showed that the main independent risk factors were broad-spectrum antibiotics,body mass index,tracheal intubation and lymphocyte count for lower respiratory tract infection in critically ill patients with neurosurgery(P＜0.05).The mortality rate(46.4 ％) of patients complicated with lower respiratory tract infection was higher than that of patients without lower respiratory tract infection(3.0 ％) after 90 days.There was statistically significant difference between both groups(x2=9.194,P =0.000).Conclusions:Neurosurgical critically patients complicated with lower respiratory tract infection were more common,especially Gram-negative bacteria.The usage of broad spectrum antibiotics,body mass index,tracheal intubation,lymphocyte count were the main risk factors,and nursing management need to be strengthened in clinic.
Keywords：traumatic brain injurylower respiratory tract infectionpathogensrisk factorsbroad-spectrum antibioticsbody mass indexendotracheal intubationlymphocyte count
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 669-672 )