Systemic evaluation on efficacy of chlorhexidine sponge bath for preventing catheter associated urinary tract infec-tions for adult patients in intensive care unit
Huang Huaping
Chen Bin
Wang Haiyan
Abstract：Objective:To evaluate the effect of daily chlorhexidine sponge bath for preventing catheter associat-ed urinary tract infections(CAUTI)in adult patients in the intensive care unit(ICU).Methods:Systematically searched PUBMED,EMBASE,the Cochrane Library and China National Knowledge Infrastructure(CNKI)from their inception to March 2015.Two reviewers independently evaluated and extracted data from included standard randomized clinical studies and experimental studies.Review Manager 5 .3 was applied to extract data for analy-sis.Results:Total of 7 papers were included in the study,including 2 randomized clinical trials and 5 experimen-tal studies.The result revealed that 471 infections were detected in a total of 39 136 patients in chlorhexidine sponge bath group.And 804 infections were detected in a total of 43 689 patients in control group.The differ-ence between two groups on CAUTI rate were statistical significant(RR=0.68,95%CI was 0.52 0.88,P=0.004). Conclusions:Daily chlorhexidine sponge bath can significantly reduce the risk of CAUTI for adult patients in ICU.While the conclusion still needs high quality clinical trials to further verify.
Keywords：chlorhexidineICUcatheter associated urinary tract infectionbathevaluation system
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 3123-3127 )