Study on relationship among pH value of gastric fluid,pepsin,bacterial colonization and respiratory infections in ICU patients in Neurosurgical department
Abstract：Objective:To know about the relationship among pH value of gastric fluid,pepsin,bacterial colonization and respiratory infections in ICU patients in Neurosurgical department,so as to provide reference for clinical effective care interventions timely.Methods:The neurosurgical ICU patients in a three grade A hospital in Beij ing city were selected for lasting 3 days on observation on patients’condition,and the gastric juice was collected for pH value,pepsin testing and bacterial culturing,and to collect tracheal secretions for bacterial culturing.Results:47 cases of patients were included and totally 235 cases times were collected,and the pH value of gastric juice was 2.5~8.0,an average of 5.54±1.02.Gastric pH value gradually increased and the acidity decreased with the increace of length of ICU stay.The pepsin content in gastric juice was 3.766 ng/mL~84.482 ng/mL,and it was negatively correlated to gastric pH value (r= 0.939,P<0.001).76.6% of patients had gastric colonization,85.1% of patients had sputum bacterial coloniza-tion,and their consistency ratio was 57.4%.Conclusion:Gastric pH monito-ring for ICU severe patients is helpful to observe the patient’s condition changes dynamicly,and timely and reasonablely regulate the gastric pH. Gastric pH control in the appropriate range is important for the treatment and prognosis of the patients.
Keywords：ICU patientsgastric juicepH valuepepsinbacterial coloniza-tionrespiratory infections
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2319-2321 )