To Control the Drug Losses of Powder Injection in the Course of Intravenous Infusion
Abstract：To approach the drug losses in the course of powder injection intravenous infusion, Sodium Cefazolin was determined in the whole course of infusion including quantitative solvent dilution, the losses of empty ampule and rinsing of infusion bottle. It was determined through ultraviolet spectrophotometry. Results showed that in the whole course of infusion, the drug loss was 0. 516 g + 0.09 g.It accounted for 12.9% of total administrative medicine. It also showed that the drug loss was more in randomly using solvent than that in quantitatively solvent dilution and rinsing the empty ampule and infusion bottle once. Suggested that when one infuse powder medicine, one would dilute powder injection with quantitative solvent according to the ampule volume. And it may decrease the drug losses if one rinsed the empty ampule or infusion bottle once.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 65-66 )