Effect of endoscopic placement of spring coils combined with tissue glue embolization in the treatment of esophageal and gastric varicose veins on patient recovery speed and gastrointestinal function

HUANG Jianbin; CHEN Zhixiang; LIN Jiejun

doi:10.3969/j.issn.2095-8331.2024.06.012

Abstract：Objective To explore the clinical effect of endoscopic placement of spring coils combined with tissue glue embolization in the treatment of liver cirrhosis with esophageal and gastric variceal bleeding.Methods The medical records of patients with liver cirrhosis accompanied by esophageal and gastric variceal rupture and hemorrhage,who were treated in Wenzhou Central Hospital from January 2019 to January 2024,were retrospectively analyzed.75 patients who were treated with endoscopic spring coil implantation combined with tissue glue embolization were included in the combination group.In addition,74 patients who were only treated with endoscopic tissue glue embolization were included in the embolization group,and the efficacy and safety of the two groups were compared.Peripheral blood hemoglobin(Hb),red blood cells(RBC),albumin(ALB),platelets(PLT),gastric varices diameter,gastrin(GAS),motilin(MTL)and length of hospital stay were different before and after treatment.Results The 3-month rebleeding rate and tissue glue dosage in combination group were lower than those in embolization group,with statistical significance(P＜0.05).3 months after surgery,the serum Hb and ALB values in the combination group were higher than those in the embolization group,with statistical significance(P＜0.05),and serum GAS and MTL levels in the combination group were lower than those in the embolization group,with statistical significance(P＜0.05).The operative complication rate of 5.33％in the combination group was not statistically different from that of 12.16％in the embolization group(P＞0.05).Conclusion Endoscopic implementation of spring coil insertion combined with tissue gel embolization for the treatment of liver cirrhosis with esophageal and gastric variceal bleeding has a lower long-term rebleeding rate,which is more conducive to the recovery of peripheral blood indicators and gastrointestinal function in patients.