Predictive value of preoperative systemic inflammation score for long-term prognosis of colorectal cancer patients treated with radical surgery
JIANG Wenliang
XUN Feng
CHENG Shaoqi
WANG Honggang
XIA Yong
Abstract：Objective This study aimed to evaluate the predictive value of preoperative Systemic Inflammatory Grade(SIG)for long-term prognosis in colorectal cancer(CRC)patients undergoing curative surgery.Methods A total of 189 CRC patients who underwent curative surgery between January 2015 and June 2018 were included.Univariate and multivariate Cox regression analyses were performed to identify factors affecting overall survival(OS),and receiver operating characteristic(ROC)curve was conducted to evaluate the predictive value of SIG.Results SIG score,neutrophil-to-lymphocyte ratio(NLR)group and modified Glasgow Prognostic Score(mGPS)were all associated with prognosis in CRC patients,with SIG having the highest predictive accuracy.Patients with higher SIG scores had lower 5-year OS rates.Conclusion SIG can serve as a valuable biomarker to predict long-term prognosis in CRC patients undergoing curative surgery.
Keywords：colorectal cancersystemic inflammatory gradelong-term prognosis
Publication Date：2024-10-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 18-23 )