Effects of Xianshanhuang compound preparation on growth performance and immune function in Trachinotus ovatus

LIU Danning; SHANG Dezhao; ZHANG Jinwu; LIANG Jing; HU Tingjun; PENG Yong; LIN Guangsong; YU Meiling

doi:10.13557/j.cnki.issn1002-2813.2026.02.009

Abstract：This experiment aimed to investigate the effects of the Xianshanhuang compound preparation on the growth performance and immune function of Trachinotus ovatus.A total of 630 healthy Trachinotus ovatus with an initial body weight of(4.57±0.31)g were selected and randomly divided into seven groups,with three replicates per group and 30 fish per replicate.The control group was fed with basic diet,while the experimental groups were added with 2.5,5.0,10.0,15.0,20.0,and 25.0 g/kg of Xianshanhuang compound preparation to the basic diet.The pre-test period was seven days,and the formal test period was 30 days.The results showed that on the 30th day of the experiment,compared with the control group,the weight gain rate(WGR)and specific growth rate(SCR)of the group 10.0 were significantly increased(P<0.05).There was no significant difference in the blood routine indicators among all groups(P>0.05).Histological sections of the liver and spleen displayed clear structures,with no significant pathological changes observed in each group.In the liver and spleen tissues of group 10.0,the expression level of tumor necrosis factor-α(TNF-α)was decreased,while the expression levels of interleukin-1β(IL-1β),nuclear factor kappa B(NF-κB),and interferon alpha-3 reverse transcription product(IFNa3-RT)were increased,but there was no significant difference(P>0.05).The study shows that feeding Trachinotus ovatus with the Xianshanhuang compound preparation at 10.0 g/kg for 30 days has no toxic or side effects,demonstrates good safety,and can improve the growth performance of Trachinotus ovatus.