Effects of Lonicera japonica Thunb.extract on intestinal health,immunity,and antioxidant capacity of Qianshao spotted pigs
YANG Qiaomei
LIAO Chanjuan
LIU Jing
YANG Yan
XIAO Biao
TAN Dezhan
Abstract：The experiment aimed to investigate the effects of different dietary levels of Lonicera japonica Thunb.extract on the intestinal microbiota,immune function,and antioxidant capacity of Qianshao spotted pigs.A total of 72 Qianshao spotted pigs with similar body weight were selected and randomly divided into four groups,with three replicates per group and six pigs per replicate.The control group was fed a basal diet,while the experimental groups were supplemented with 0.05％(0.05％group),0.10％(0.10％group),and 0.20％(0.20％group)Lonicera japonica Thunb.extract based on the basal diet,respectively.The pre-test period was seven days,and the formal test period was 56 days.The results showed that there was no significant difference in the Alpha diversity indexes of intestinal microbiota among groups(P＞0.05),but the Chao1 index of supplemented groups showed an increasing trend.Compared with the control group,the relative abundance of Escherichia coli and Streptococcus were significantly decreased in 0.10％and 0.20％groups(P＜0.05),while the relative abundance of Lactobacillus was significantly increased in all supplemented groups(P＜0.05).The intestinal microbiota of Qianshao spotted pigs was primarily composed of Firmicutes,Bacteroidota,and Proteobacteria.The relative abundance of Proteobacteria was significantly reduced in 0.10％and 0.20％groups(P＜0.05),and the relative abundance of Spirochaetota was also significantly decreased in 0.10％group(P＜0.05).Compared with the control group,the serum concentrations of interferon-γ(IFN-γ),interleukin-10(IL-10),and immunoglobulin G(IgG)were significantly increased in 0.10％group(P＜0.05),while the content of interleukin-6(IL-6)was significantly decreased(P＜0.05).The total antioxidant capacity(T-AOC)and superoxide dismutase(SOD)activity in 0.10％group were significantly higher than those in the control group(P＜0.05).The study demonstrates that dietary supplementation with Lonicera japonica Thunb.extract can modulate the intestinal microbiota structure,improve intestinal health,enhance immune function and antioxidant capacity in Qianshao spotted pigs,with the most effective results observed at an inclusion level of 0.10％.
Keywords：Lonicera japonica Thunb.extractintestinal healthimmunityantioxidantQianshao spotted pigs
Publication Date：2025-10-16
Online Publishing Date：2025-12-09(First online date of this platform, not the publication date of the document)
Pages：5( 37-41 )