Optimize preparation technology of essential oil from Zanthoxylum bungeanum Maxim microencapsule with response surface analysis
DENG Yueting
HAN Dong
ZHAO Xiaoliang
ZHU Tianke
WANG Kaibin
LIU Yuan
ZHANG Weijie
Abstract：The experiment aimed to optimize the preparation process of Zanthoxylum bungeanum Maxim essential oil microencapsule.Using gelatin and sodium alginate as wall materials,Zanthoxylum bungeanum Maxim essential oil microencapsule is prepared by the complex coacervation method.Single-factor experiments were conducted to investigate the effects of the gelatin-to-sodium alginate ratio,reaction pH value,wall material concentration,emulsifier dosage,and stirring speed on microencapsule formation.The encapsulation efficiency of the microencapsule was used as the evaluation index,and response surface methodology was employed to determine the optimal preparation conditions for the Zanthoxylum bungeanum Maxim essential oil microencapsule.The results showed that when the ratio of gelatin-to-sodium alginate was 4:1,the reaction pH was 4.55,the wall material concentration was 1.773％,the emulsifier dosage was 1.27％,and the stirring speed was 743 r/min,the encapsulation efficiency of the prepared Zanthoxylum bungeanum Maxim essential oil microencapsule was the highest,reaching 88.13％,and the essential oil microencapsule could achieve sustained release of Zanthoxylum bungeanum Maxim essential oil.The study indicates that the complex coacervation method used in the experiment yields microencapsule with high encapsulation efficiency and excellent sustained-release properties.This process provides reference for the future development of novel essential oil formulations for the treatment of bovine mastitis.
Keywords：response surface methodologyZanthoxylum bungeanum Maxim essential oilmicroencapsule
Publication Date：2025-07-28
Online Publishing Date：2025-09-18(First online date of this platform, not the publication date of the document)
Pages：7( 83-89 )